Clinical correlations between catheter-induced urinary tract uropathogens complicating acute pyelonephritis in patients admitted in a teaching hospital
DOI:
https://doi.org/10.65221/0122Keywords:
Bacteria, catheter, urine culture, upper UTI, acute pyelonephritiAbstract
Mixed Gram-positive bacteria are common isolates, and if left untreated, they can lead to acute and progressive renal damage. This study aims to determine the prevalence and patterns of common bacterial isolates in patients with nosocomial acute pyelonephritis. The study was a cross-sectional descriptive study of 215 patients on in-dwelling catheters. Fifty patients who developed clinical acute pyelonephritis were screened. Catheter urine and tip specimens were collected and sent for microscopic culture and sensitivity testing on MacConkey, CLED, and Blood agar. Data were analyzed using SPSS Statistics version 23.0. A p-value <0.05 was considered statistically significant. Fifty patients with clinical and urine culture-positive results were analyzed. The prevalence of acute pyelonephritis was 23.3%, with 44 (88.0%) males preponderant. The average catheter duration was 6.4+-4.9 days, and was significantly associated with the occurrence of microbial agents. The most common uropathogen identified was Escherichia coli. The study revealed that a significant number of patients who developed clinical acute pyelonephritis upon admission were associated with both the underlying aetiopathogenesis and the duration of catheterization. Therefore, prompt surveillance and timely management of patients with catheter-associated urinary tract infections (CAUTIs) are essential to prevent recurrent acute pyelonephritis and subsequent renal damage.
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